RALEIGH, N.C. —  Dunk City is long gone. Make way for the next bunch of bracket busters from the little-known Atlantic Sun Conference: Mercer.

The 8,300-student school from Macon, Ga., delivered the biggest shocker in an already topsy-turvy NCAA tournament on Friday, going into Duke’s backyard and knocking off the No. 3 seed Blue Devils 78-71.

“This,” Atlantic Sun player of the year Langston Hall said, “is what March Madness is all about.”

The 14th-seeded Bears — with a starting lineup of five seniors — came back from five points down in the last 4:52 as Duke’s offense collapsed.

They sent home one of the true blue-blood programs, coached by Hall of Famer Mike Krzyzewski and starring freshman Jabari Parker, sure to be one of the top NBA picks this year. Mercer is coached by former Oklahoma Baptist player Bob Hoffman, who has banged around the coaching ranks from women’s teams to the American Basketball Association to the Rio Grande Valley Vipers of the NBA Developmental League.

Jakob Gollon scored 20 points and Daniel Coursey scored 17, helping the Bears overcome a season-high 15 3-pointers from Duke.

Mercer qualified for its first NCAA tournament since 1985 by winning the Atlantic Sun conference championship over Florida Gulf Coast, nicknamed “Dunk City” for the team’s above-the-rim offense. A year earlier, the Bears lost that game and watched FGCU advance to the Sweet 16.

“When they were going on their run, we were sitting at home thinking, ‘Man, that could have been us,’” Anthony White Jr. said.

Now it is.

Mercer scored 11 straight points during the late 20-5 run that clinched the biggest victory in school history and sent the Blue Devils to their second first-game exit in three years.

Quinn Cook scored 23 points and Rasheed Sulaimon added 20 for Duke.

But their defense — an uncharacteristic weakness all season — did them in again while all those Mercer seniors simply got any shot they wanted. The Bears shot 56 percent — 58 percent in the second half.

“They’re a team that’s been together a long time,” Duke forward Rodney Hood said. “They sliced us up. There’s no other way to put it.” 

WICHITA STATE 64, CAL POLY 37

ST. LOUIS — Cleananthony Early had 23 points and unbeaten Wichita State faced no resistance from Cal Poly, going to 35-0 for the best start in NCAA history with a rout of Cal Poly.

The Shockers (35-0) dominated from the tip-off against the only team with a sub-.500 record in the tournament. With the exception of Early, most of the glaring numbers were on defense. The losers managed 13 points in the first half and shot 21 percent.

Malik Love had nine points for Cal Poly (14-20), which won the Big West tournament as the No. 7 seed and beat Texas Southern in First Four game before being held to a season low for points. Chris Eversley, the Big West tourney MVP and coming off a 19-point game, was held to six points on 2-for-14 shooting. 

TENNESSEE 86, MASSACHUSETTS 67

RALEIGH, N.C.— Jarnell Stokes scored a career-high 26 points and grabbed 14 rebounds to lead Tennessee.

Jordan McRae added 21 points for the Volunteers (23-12), the No. 11 seed in the Midwest Regional. Tennessee had little trouble with the sixth-seeded Minutemen (24-9), shooting 54 percent from the field and handling UMass’ fullcourt pressure in a surprisingly one-sided performance that included another solid defensive showing.

The Vols are in the NCAAs for the first time in three seasons, starting with a First Four overtime win against Iowa.

Chaz Williams and Maxie Esho scored 12 points each for UMass in its first NCAA appearance since 1998. The Minutemen fell behind by double figures early, trailed by 20 points before halftime and never got closer than 10 again.

WICHITA STATE 64, CAL POLY 37

ST. LOUIS — Cleananthony Early had 23 points and unbeaten Wichita State faced no resistance from Cal Poly, going to 35-0 for the best start in NCAA history.

The top-seeded Shockers (35-0) dominated from the opening tip against the only team with a losing record in the tournament. With the exception of Early, most of the glaring numbers were on defense. The losers managed 13 points in the first half and shot 21 percent.

Malik Love had nine points for Cal Poly (14-20), which won the Big West tournament as the No. 7 seed and beat Texas Southern in First Four game before being held to a season low for points. Chris Eversley, the Big West tourney MVP and coming off a 19-point game, was held to six points on 2-for-14 shooting.

KENTUCKY 56, KANSAS STATE 49

ST. LOUIS — Julius Randle had 19 points and 15 rebounds, Aaron Harrison finished with 18 points and No. 8 seed Kentucky held off Kansas State to earn a date with Wichita State in the next round.

The preseason No. 1, Kentucky (25-10) is finally starting to live up to the expectations that came with its heralded recruiting class. John Calipari’s bunch nearly knocked off Florida in the SEC title game last week and seemed to carry that momentum right into the Scottrade Center.

Marcus Foster had 15 points, Shane Southwell scored 11 and Thomas Gipson finished with 10 for Kansas State (20-13), which started in a 1-0 hole after a technical for a dunk in pregame warmups. The No. 9 seed then struggled to hit from the perimeter against Kentucky’s tall lineup.

Kansas State was just 5 of 21 from 3-point range. Foster was 1 of 7.

STANFORD 58, NEW MEXICO 53

ST. LOUIS — Chasson Randle scored 23 points and Stanford made an impression in its first NCAA appearance since 2008.

The 10th-seeded Cardinal (22-12) built an early 16-point lead then held on after No. 7 seed New Mexico rallied to tie it midway through the second half. They got four crucial free throws from reserve Robbie Lemons and Randle in the final half-minute after New Mexico had cut the deficit to two points.

Cameron Bairstow had 24 points and eight rebounds but the Lobos (27-7) got off-days from their other top threats. Kendall Williams and Alex Kirk, who together average 30 points, combined for just six. 

KANSAS 80, EASTERN KENTUCKY 69

ST. LOUIS — Andrew Wiggins scored 19 points, Jamari Traylor and Perry Ellis had double-doubles and second-seeded Kansas pulled away down the stretch to beat pesky Eastern Kentucky.

Traylor finished with 17 points and 14 rebounds, and Ellis had 14 points and 13 boards for the Jayhawks (25-9), who trailed 56-53 with 9 minutes to go before their game-ending charge.

Glenn Cosey hit five 3-pointers and had 17 points for the 15th-seeded Colonels (24-10), the Ohio Valley Conference champions. Tarius Johnson and Eric Stutz finished with 15 points apiece. 

STEPHEN F. AUSTIN 77, VIRGINIA COMMONWEALTH 75, OT

SAN DIEGO — Desmond Haymon scored on an improbable four-point play with 3.6 seconds in regulation and hit a big 3-pointer in overtime to lead No. 12 seed Stephen F. Austin to a win over fifth-seeded Virginia Commonwealth.

VCU (23-10) was firmly in control for most of the second half before SFA (32-2) rallied in the closing seconds.

Haymon hit one of the biggest — and most improbable — shots of what’s already been a wild March, knocking down a 3-pointer and a free throw after being fouled by Jordan Burgess at the end of regulation.

Haymon hit another 3-pointer to put SFA up with 2 minutes left, but VCU had a final shot after Thomas Walkup missed 1 of 2 free throws with 14 seconds left. JeQuan Lewis got an open 3-pointer, but it went long and SFA snared the rebound. 

BAYLOR 74, NEBRASKA 60

SAN ANTONIO — Cory Jefferson scored 16 points and sixth-seeded Baylor kept 11th-seeded Nebraska winless in its NCAA tournament history.

The Bears (25-11) have won 11 of 13 after a dismal start in the Big 12, recapturing the kind of momentum that vaulted the Bears to the Elite Eight in 2010 and 2012.

Terran Petteway scored 18 points for Nebraska (19-13), which fell to 0-7 in tournament history.

The Cornhuskers hadn’t played on this stage since 1998 and often looked like it. Frustration boiled over for Big Ten coach of the year Tim Miles, who was ejected with 11 minutes left. 

CREIGHTON 76, LOUISIANA-LAFAYETTE 66

SAN ANTONIO — Doug McDermott scored 30 points and third-seeded Creighton got three huge 3-pointers in the second half from Ethan Wragge to beat Louisiana-Lafayette.

McDermott had a double-double by halftime but went scoreless for nearly 14 minutes of the second half, leaving it to Wragge’s long shots to bail out the Bluejays from a potential upset by the Ragin’ Cajuns, who attacked Creighton (27-7) with fearless defense and rebounding.

Elfrid Payton scored 24 points for Sun Belt tournament champion Louisiana-Lafayette (23-12), which led 50-48 before Wragge struck from long range to turn the momentum.

McDermott came into the tournament averaging 26.9 points per game and ranks fifth in NCAA history in career points. He has scored at least 30 points in four of Creighton’s last five games.

ARIZONA 68, WEBER ST. 59

SAN DIEGO — Nick Johnson scored 18 points and Aaron Gordon added 16 as top-seeded Arizona overcame a shaky start and a late run by Weber State.

Arizona (31-4) fell into an eight-point deficit in the opening minutes to give the 16th-seeded Wildcats hope of a monumental upset.

The desert Wildcats tried to squash the dream quickly with two big second-half runs, but Weber State fought its way back from a 21-point deficit to make it close in the second half.

Arizona blocked 12 shots, held Weber State to 30 percent shooting and made 55 percent of its shots.

Davion Berry had 24 points to lead Weber State (19-12) in its first NCAA tournament appearance since 2007. 

GONZAGA 85, OKLAHOMA ST. 77

SAN DIEGO — Kevin Pangos scored 26 points and Gary Bell Jr. added 17 for eighth-seeded Gonzaga, which beat Marcus Smart and ninth-seeded Oklahoma State.

The Bulldogs (29-6) are in their 16th straight NCAA tournament.

The refs called 61 fouls, and five players fouled out. Pangos made 12 of 14 free throws, most of them in the closing minutes.

Smart had 23 points, 13 rebounds, seven assists and six steals for Oklahoma State (21-13). The Cowboys won five of seven games coming in, a run that coincided with Smart’s returning from a three-game suspension for shoving a Texas Tech fan. 

NORTH CAROLINA 79, PROVIDENCE 77

SAN ANTONIO — James Michael McAdoo sank two free throws in the final 3.5 seconds, and No. 6 seed North Carolina rallied to beat 11th-seeded Providence.

Providence’s Bryce Cotton scored a career-high 36 points and made one dazzling shot after another down the stretch. But he also fumbled a long rebound in the final moments, robbing the Friars of a chance for a last-second miracle.

Had North Carolina (24-9) lost, it would’ve been the first time since 1979 the Tar Heels and rival Duke lost on the same day of the tournament.

The Blue Devils fell earlier to 14th-seeded Mercer, and the Friars nearly handed North Carolina a similar stunner.

Marcus Paige led North Carolina with 19 points. 

IOWA STATE 93, NC CENTRAL 75

SAN ANTONIO — Georges Niang scored 24 points, but also broke his foot and will miss the rest of the NCAA tournament, as No. 3 seed Iowa State pulled away from 14th-seeded North Carolina Central in the second half.

The Big 12 tournament champions found themselves in an early struggle with a program making its first NCAA tournament appearance in just its third year as a full-time Division I program. But the Cyclones’ quickness and balance eventually took over.

Iowa State (27-7) had five players score in double figures. Niang’s two 3-pointers early in the second half keyed the run that put the game away.

After the game, the Cyclones announced on Twitter: “Georges Niang has a foot fracture and will miss the remainder of the season.”

Jeremy Ingram scored 28 for North Carolina Central (28-6), which came in on a 20-game win streak and won the Mid-Eastern Athletic Conference.

VIRGINIA 70, COASTAL CAROLINA 59

Anthony Gill scored 17 points to help No. 1 seed Virginia pull away late and beat Coastal Carolina, avoiding a historic upset.

The Cavaliers trailed by 10 in the first half and five at halftime to the 16th-seeded Chanticleers before pushing ahead for good with about 9 minutes left.

A No. 16 seed has never beaten a No. 1 since the tournament expanded to 64 teams in 1985, and the Cavs (29-6) ensured history would wait at least another year.

Evan Nolte came off the bench and hit two huge 3-pointers to help Virginia finally push away from the Big South champion Chanticleers (21-13), who were in the tournament for the first time in 21 years.

The game was tied at 47 before Nolte’s 3s powered a 23-7 spurt that finally put the game away.

Virginia advanced to Sunday’s third round to face No. 8 seed Memphis.

MEMPHIS 71, GEORGE WASHINGTON 66

RALEIGH, N.C. — Michael Dixon Jr. scored 19 points and hit four free throws in the final 10 seconds to help Memphis hold off George Washington in the second round of the East Regional.

Joe Jackson added 15 points for the eighth-seeded Tigers (24-9). They entered the tournament having lost three of five to fall out of the national rankings, and shot 49 percent in this one but struggled to put the ninth-seeded Colonials away until the final seconds.

Isaiah Armwood scored a season-high 21 points after playing the final 12 minutes with four fouls for ninth-seeded GW (24-9), which was just 2 of 12 from 3-point range yet never fell behind by more than 10 points.

Leading scorer Maurice Creek — who averages 14 points — finished with nine on 2-of-13 shooting for GW, but he airballed a 3-pointer in the final seconds that would have tied it.