LOS ANGELES — A growing list of Democratic presidential contenders want the U.S. government to legalize marijuana, reflecting a nationwide shift as more Americans look favorably on cannabis.

Making marijuana legal at the federal level is the “smart thing to do,” says California Sen. Kamala Harris, a former prosecutor whose home state is the nation’s largest legal pot shop.

New Jersey Sen. Cory Booker, a prominent legalization advocate on Capitol Hill, says the war on drugs has been a “war on people.”

Former Texas U.S. Rep. Beto O’Rourke, who appears poised to join the 2020 Democratic field, has written a book arguing marijuana legalization would hobble drug cartels. In an email to supporters last week, he called again to end the federal prohibition on marijuana.

“Who is going to be the last man – more likely than not a black man – to languish behind bars for possessing or using marijuana when it is legal in some form in more than half of the states in this country?” O’Rourke wrote.

It’s a far different approach from the not-so-distant past, when it was seen as politically damaging to acknowledge smoking pot and no major presidential candidate backed legalization.

In 1992, then-White House candidate Bill Clinton delivered a famously tortured response about a youthful dalliance with cannabis, claiming he tried it as a graduate student in England but “didn’t inhale.” And two decades before that, President Richard Nixon unleashed a war on marijuana and other drugs and it helped carry him to a second term.

This year, leading Democrats hold similar positions supporting legalization. Presidential hopefuls in the Senate who have co-sponsored Booker’s legislation to end the federal prohibition include Harris, New York’s Kirsten Gillibrand, Elizabeth Warren of Massachusetts and Vermont’s Bernie Sanders, who campaigned on decriminalizing pot in his 2016 presidential bid.

Another 2020 Democratic candidate, Minnesota Sen. Amy Klobuchar, supports legalization and believes states should have the right to determine how to handle marijuana regulation within their borders but hasn’t signed on to Booker’s legislation.

Washington Gov. Jay Inslee, who entered the contest this month, said in his announcement speech it’s “about time” to legalize the drug nationally.