CLEVELAND — Kyler Murray threw four touchdown passes as the Arizona Cardinals remained the NFL’s only unbeaten team and continued their best start since 1974 – without Coach Kliff Kingsbury on Sunday – with a 37-14 win over the battered and reeling Cleveland Browns.

The Cardinals (6-0) built a 20-0 lead in the first half and kept their perfect record intact despite not having Kingsbury or star linebacker Chandler Jones, who both tested positive for COVID-19 this week.

Murray connected with DeAndre Hopkins for two TDs, and Arizona’s shifty quarterback came up with a clutch play whenever the Cardinals needed one.

The Browns (3-3) have lost two straight under Coach Kevin Stefanski for the first time, and Cleveland has bigger concerns, most notably to a growing list of major injuries. The latest was to running back Kareem Hunt, who was carted to the locker room in the fourth quarter because of a calf injury.

Cleveland was already missing star running back Nick Chubb (calf) and played without both starting offensive tackles. Also, quarterback Baker Mayfield appeared to reinjure his left shoulder and wide receiver Odell Beckham Jr. briefly left because of a shoulder issue. Mayfield committed three turnovers: two fumbles and an interception.

JAGUARS 23, DOLPHINS 20: Jacksonville (1-5) ended its 20-game losing streak when Matthew Wright kicked a 53-yard field goal as time expired in a victory over Miami (1-5) in London.

Trevor Lawrence connected on a short slant pass to Laviska Shenault Jr. and the Jags called timeout with 1 second remaining after the Dolphins gambled on a fourth-and-1 from their 46 and came up short.

Lawrence threw for 319 yards and a touchdown as he and Coach Urban Meyer finally earned their first NFL victories – even if it required a trip to Europe to get it done in a “home” game at Tottenham Hotspur Stadium.

The Dolphins lost their fifth consecutive game, spoiling the return of Tua Tagovailoa, who made his first start in a month. The second-year quarterback threw two touchdown passes to Jaylen Waddle.

RAVENS 34, CHARGERS 6: Lamar Jackson threw for 167 yards and a touchdown, and Baltimore (5-1) frustrated Justin Herbert in a win at home against Los Angeles (4-2).

A week after scoring 47 points against Cleveland, the Chargers came up empty on their first five possessions and were held under 16 points for only the second time since drafting Herbert before last season.

The Ravens completely controlled this matchup of division leaders. Each of Baltimore’s three veteran running backs – Latavius Murray, Le’Veon Bell and Devonta Freeman – scored a touchdown.

Jackson went 19 for 27 with two interceptions. Herbert was 22 of 39 for 195 yards with a touchdown and an interception.

RAMS 38, GIANTS 11: Matthew Stafford threw three of his four touchdown passes in a 28-point second quarter, and Los Angeles (5-1) rolled to a victory over injury-plagued and error-prone New York (1-5) in East Rutherford, New Jersey.

Stafford connected with prime target Cooper Kupp on scoring passes of 3 and 13 yards. He also found Robert Woods for a 15-yard score and running back Darrell Henderson on a 25-yarder.

Stafford, who has 16 TD passes in six games, finished 22 of 28 for 251 yards in three-plus quarters. The Rams took advantage of two short fields provided by their defense for easy TDs in breaking the game open early.

CHIEFS 31, WASHINGTON 13: Patrick Mahomes threw for 397 yards and engineered three second-half touchdown drives to compensate for a pair of interceptions, leading Kansas City (3-3) to a comeback victory over Washington (2-4) in Landover, Maryland.

After throwing two picks before halftime, Mahomes connected with Tyreek Hill on a 2-yard touchdown pass late in the third quarter. He put the game out of reach with a 24-yarder to Demarcus Robinson with 3:14 left in the fourth. In between, new starting running back Darrel Williams rushed for his second TD of the game.

The defense also finally played its part, holding an opponent under 29 points for the first time this season. The Chiefs forced a fumble and then picked off Taylor Heinicke to seal the win.

COLTS 31, TEXANS 3: Carson Wentz threw two touchdown passes, Jonathan Taylor ran for two more and the Indianapolis defense held up in the second half Sunday as the Colts (2-4) blew out visiting Houston (1-5).

Indy rebounded from an embarrassing fourth-quarter collapse at Baltimore by winning for the second time in three weeks.

Houston has lost five straight overall, and six of the last seven against the Colts.

PACKERS 24, BEARS 14: Aaron Rodgers threw for two touchdowns and ran for another, leading Green Bay (5-1) to a win at Chicago (3-3).

The Packers beat the Bears for the 20th time in 23 games counting the playoffs and improved to 22-5 with Rodgers as the starter against Chicago. They also prevented Chicago from tying them for the NFC North lead.

BENGALS 34, LIONS 11: Joe Burrow tied a career high with three touchdown passes, helping visiting Cincinnati (4-2) rout Detroit (0-6).

The Bengals have already equaled last year’s number of wins, and have doubled their victories from 2019 during Coach Zac Taylor’s debut season.

VIKINGS 34, PANTHERS 28: Kirk Cousins completed a 27-yard touchdown pass to K.J. Osborn on the first possession of overtime to lift Minnesota (3-3) to a win at Carolina (3-3).

Cousins threw for 373 yards and three touchdowns against the league’s top-ranked pass defense, Dalvin Cook ran for 140 yards and a score, and the Vikings finally solved their second-half offensive woes. Adam Thielen had several big catches, finishing with 11 receptions for 126 yards and a touchdown.

RAIDERS 34, BRONCOS 24: Derek Carr sliced up the Denver defense for 341 yards and two touchdowns, Maxx Crosby made three sacks and Las Vegas (4-2) started the post-Jon Gruden era by thrashing of the Broncos (3-3) in Denver.

The Raiders (4-2) gave longtime special teams coordinator Rich Bisaccia a win in his debut as interim head coach, and offensive coordinator Greg Olson was masterful in his first play-calling duties for Las Vegas since Carr’s rookie season in 2014.

STEELERS 23, SEAHAWKS 20: Chris Boswell hit a 36-yard field goal with 2:50 left in overtime to give Pittsburgh (3-3) a victory at home against Seattle (2-4).

Boswell’s third field goal of the game came three plays after Steelers outside linebacker T.J. Watt forced Seattle quarterback Geno Smith to fumble deep in Seahawks territory. Pittsburgh inside linebacker Devin Bush scooped it up to give the Steelers possession. Two snaps to center the ball in the middle of the field set up Boswell to win it.

Pittsburgh won its second straight thanks in large part to Watt, who collected two of his team’s five sacks and helped the defense right itself after a third-quarter swoon let the Seahawks rally from a 14-point halftime deficit.

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