BALTIMORE  — Kyle Tucker’s grand slam off Félix Bautista in the top of the ninth inning gave the Houston Astros a 7-6 victory over the Baltimore Orioles on Tuesday night.

Houston trailed 5-0 after Ryan Mountcastle and Adley Rutschman homered off Framber Valdez in the first and second innings, but the Astros pulled off a remarkable comeback in the ninth against arguably the game’s most dominant closer.

Pinch-hitter Jon Singleton led off the ninth with a walk, and Jose Altuve followed with a single. Bautista (6-2) struck out Alex Bregman, but Yordan Alvarez came within a few feet of tying it with a drive to center. Jorge Mateo — a shortstop making only his second start of the year in center field — robbed Alvarez of an extra-base hit earlier in the game, but he couldn’t catch this one, and the ball bounced off the wall for a very long single.

Tucker then battled Bautista for nine pitches, finally hitting a 100 mph fastball to right-center field for his 20th home run of the year. Bautista had allowed only five earned runs all season before Houston scored four on him in two-thirds of an inning.

Baltimore’s lead over Tampa Bay atop the AL East dropped to two games.

TIGERS 6, TWINS 0: Eduardo Rodriguez pitched seven solid innings, and Detroit stopped visiting Minnesota’s five-game winning streak.

Rodriguez (8-5) allowed four hits — all singles — struck out five and walked three. The veteran left-hander, who was nearly traded to the Los Angeles Dodgers at the deadline, improved to 4-1 with a 3.63 ERA in his last seven starts.

Tigers slugger Miguel Cabrera went 2 for 4 and scored a run.

GUARDIANS 1, BLUE JAYS 0: Tanner Bibee pitched seven innings and Ramón Laureano drove in the game’s only run in his Cleveland debut, giving the Guardians a win at home.

Bibee (8-2) allowed six singles — three by Whit Merrifield — and remained unbeaten in his last nine starts. The right-hander struck out six and showed a veteran’s poise in working out of a bases-loaded jam.

Laureano, claimed off waivers on Monday from Oakland, hit an RBI double in the second inning off Yusei Kikuchi (9-4), who gave up three hits in seven innings.

NATIONAL LEAGUE

PHILLIES-NATIONALS SPLIT: Joey Meneses’ second homer of the game was a solo shot off Phillies All-Star closer Craig Kimbrel in the ninth inning that gave visiting Washington a 5-4 win over Philadelphia and a doubleheader split.

Kyle Schwarber homered twice to reach 30 for the season, drove in five runs and led the Phillies to an 8-4 win in the opener.

MARLINS 3, REDS 2: Jorge Soler hit a two-run homer in the seventh inning and visiting Miami rallied for a win over Cincinnati Reds in a matchup of NL wild-card contenders.

CUBS 3, METS 2: Mike Tauchman hit a tie-breaking homer in the eighth inning and Jameson Taillon retired his final 16 batters to win his fourth straight start as Chicago won at New York.

Cody Bellinger also went deep and Yan Gomes had an RBI double for the surging Cubs, who won for the 16th time in 21 games.

BRAVES 8, PIRATES 6: Orlando Arcia’s two-run double with two outs in the top of the ninth capped a three-run inning and rallied MLB-best Atlanta to a win at Pittsburgh  after star right fielder Ronald Acuña Jr. left the game.

Acuña was hit on the left elbow by a pitch from reliever Colin Holderman in the sixth inning and was removed for a pinch runner. X-rays were negative and Acuna is considered day to day.

INTERLEAGUE

RAYS 4, CARDINALS 2: Yandy Díaz, Brandon Lowe and Randy Arozarena hit RBI singles in the eighth inning and Tampa Bay beat visiting St. Louis.

Díaz went 4 for 4 and raised his average from .315 to .322 as the Rays improved to 7-3 over their last 10 games. Isaac Paredes hit his 22nd homer of the season in the seventh inning.

NOTES

TIGERS: Jim Price, a former Detroit Tigers catcher who played on their 1968 championship team and a broadcast analyst for decades, has died. He was 81.

The Tigers announced his death. No cause was given.

Price played for the Tigers from 1967 to 1971, backing up All-Star and Gold Glove-winning catcher Bill Freehan. He hit .214 with 18 homers and 71 RBI in 261 career games and played for Detroit’s 1968 World Series championship team.

He began working as an analyst on radio broadcasts for the Tigers in 1998 and later was a part of their TV coverage.

RAYS: All-Star left-hander Shane McClanahan’s may not pitch again this season.

Rays Manager Kevin Cash said McClanahan will have his arm evaluated soon but it is “highy unlikely” that he will pitch again this season.

Cash said Tommy John surgery is among the options under consideration.

McClanahan (11-2) left his last start on Aug. 2 in New York against the Yankees with tightness in his left forearm. He pitched four innings and gave up five runs. The 26-year-old has pitched five innings or fewer in five of his last six starts.

McClanahan is scheduled to be examined by Dr. Keith Meister on Monday.

BLUE JAYS: The Toronto Blue Jays placed center fielder Kevin Kiermaier on the 10-day injured list after he cut his arm making a leaping catch against the wall in Boston on Sunday.

Kiermaier needed eight stitches to close the gash on his right forearm. In the sixth inning, Kiermaier raced back and jumped against the center-field wall to rob Red Sox infielder Luis Urías of extra bases.

But in making the grab, Kiermaier’s arm scraped against a metal screen, causing the laceration.

To take his spot, the Blue Jays recalled outfielder Nathan Lukes from Triple-A Buffalo.

The Blue Jays also got good news on starter Hyun Jin Ryu, who was struck on the right knee by a liner in Monday’s win.

X-rays on Ryu were negative. The left-hander was making just his second start after undergoing Tommy John surgery last year. Ryu is expected to make his next start on Sunday.

MARINERS: The Seattle Mariners placed rookie right-hander Bryan Woo on the 15-day injured list with inflammation in his right forearm.

Seattle is expected to fill Woo’s spot in the starting rotation by promoting top pitching prospect Emerson Hancock from Double-A Arkansas.