NEW YORK — The last-place New York Yankees lost their fifth straight game as Yoshi Tsutsugo hit a tiebreaking double off Gerrit Cole in the seventh inning that lifted the Tampa Bay Rays to a 4-2 win Sunday and a three-game sweep.

Four pitchers combined on the Rays’ second three-hitter of a series in which New York managed 11 hits in all.

Cole (2-1) was hurt by slipshod defense that made three mistakes in the third inning alone, two by center fielder Aaron Hicks and one by left fielder Clint Frazier.

One of the three runs off Cole was unearned, giving the Yankees a major league-high 10 unearned runs allowed.

Joey Wendle added a ninth-inning home run off Darren O’Day, prompting more boos from the crowd of 10,606, who saved their loudest jeers for the final out.

Tampa Bay has won 16 of its last 21 against the Yankees, including in last year’s Division Series.

New York has lost five straight for the first time since Sept. 4-8, getting outscored 30-14. The Yankees have started 5-10 for the first time since 1997, when they finished second to Baltimore at 99-66.

Aaron Judge struck out three times and is 4 for his last 28, Hicks has 1 hit in his last 15 at-bats, Gleyber Torres 3 for his last 24 and Giancarlo Stanton, despite a second-inning home run, is 3 for his last 26. Clint Frazier is 1 for his last 24 and does not have an RBI in 40 plate appearances this season.

The Rays swept a series for the second time in their last three visits to Yankee Stadium after sweeping just two of their previous 51 series of three games or more in the Bronx.

ROYALS 2, BLUE JAYS 0: Salvador Perez tapped his bat twice on the plate to make sure it wasn’t cracked, then sent the next pitch he saw from Toronto reliever T.J. Zeuch into the left-field fountains, breaking open a scoreless game and sending Kansas City to a win at home.

Brady Singer kept the Blue Jays off the board through six innings. Kyle Zimmer (1-0) and Josh Staumont each worked a perfect inning, and Greg Holland finished off the two-hitter for his second save of the season.

Kansas City has won a major league-leading 55 consecutive games when ahead after seven innings.

RANGERS 1, ORIOLES 0: Nate Lowe singled with two outs and the bases loaded in the 10th inning, giving Texas a victory in Arlington, Texas.

The hit ended a five-game home losing streak for the Rangers and capped a wild extra frame that looked it would start with a lead for the Orioles, who dropped to 6-3 on the road.

In the top of the 10th, with automatic runner Maikel Franco on third base and one out, pinch-hitter Trey Mancini lined a one-hopper in front of right fielder Adolis García.

Franco, however, held up near third and was thrown out at home when catcher Jose Trevino caught García’s one-hop throw just up the line.

ATHLETICS 3, TIGERS 2: Matt Olson scored from second base on a fielding error by Detroit third baseman Jeimer Candelario with two outs in the bottom of the ninth inning as Oakland rallied for its eighth straight win.

Sean Murphy hit a tying home run in the eighth as the A’s swept the four-game series.

MARINERS 7, ASTROS 2: Ty France hit a two-run homer, and six Seattle pitchers combined on a one-hitter at home against depleted Houston.

The loss was Houston’s seventh in its last eight games and comes with five players – including four starters – still on the injured list because of COVID-19 concerns.

NATIONAL LEAGUE

PADRES 5, DODGERS 2: Eric Hosmer delivered the tying and go-ahead RBI in the seventh and eighth innings, helping San Diego beat visiting Los Angeles to avoid a sweep in the first series of the year between the NL West rivals.

Dodgers starter Trevor Bauer handed off a 2-1 lead to Los Angeles’ bullpen after six innings in tight duel with another Cy Young Award winner, Blake Snell.

Hosmer doubled home the tying run in the seventh off Brusdar Graterol, then delivered the decisive blow in the eighth. San Diego scored three unearned runs stemming from shortstop Corey Seager’s throwing error. Hosmer’s sharp single made it 3-2, and Tommy Pham followed with a two-run double into the left-field corner.

San Diego had lost seven straight in the rivalry, including a three-game sweep in last year’s NL Division Series.

BRAVES 13, CUBS 4: Freddie Freeman crushed one of Atlanta’s four homers in the first inning against Kyle Hendricks, leading the Braves to a potentially costly victory in Chicago.

Travis d’Arnaud, Ehire Adrianza and Guillermo Heredia also connected during Atlanta’s fast start, and Heredia added his first career grand slam in the sixth for his first multihomer game.

But the Braves’ offensive performance was overshadowed by the status of Ronald Acuña Jr., who left the game in the fourth inning because of pain in his lower abdominal muscles.

DIAMONDBACKS 5, NATIONALS 2: Madison Bumgarner had his best outing of the season, allowing a run over five innings as Arizona won in Washington after Nationals starter Stephen Strasburg was a late scratch.

Bumgarner (1-2) gave up just two hits and dropped his ERA from 11.20 to 8.68 through four starts. He struck out five and walked one, helping Arizona split the four-game series.

Strasburg was placed on the 10-day injured list because of right shoulder inflammation. He felt discomfort after a bullpen session during the week, and later an MRI later revealed inflammation. Manager Dave Martinez said there was no timetable for his return.

PHILLIES 2, CARDINALS 0: Aaron Nola struck out 10 and threw a two-hitter for his first nine-inning shutout in the majors, leading host Philadelphia to a win over St. Louis.

Bryce Harper homered and had three hits for the Phillies.

Nola threw a pair of doubleheader-shortened complete games last season, including a shutout. But he never pitched into the ninth inning over his first 142 career starts.

GIANS 1, MARLINS 0: Alex Wood pitched five innings in his season debut and four relievers completed a three-hitter, and San Francisco got an unearned run to avert a series sweep in Miami.

Wood, returning from a back problem that sidelined him midway through spring training, allowed three hits and walked none. The left-hander signed a $3 million, one-year contract after pitching for the Los Angeles Dodgers in 2020.

Tyler Rogers pitched a perfect ninth for his first save to complete the Giants’ third shutout in their last seven games. Closer Jake McGee, who blew a save in San Francisco’s 10-inning loss Saturday night, went on the injured list Sunday because he was feeling lingering effects from the COVID-19 vaccine.

The Giants retired the last 13 batters.

PIRATES 6, BREWERS 5: Colin Moran hit an early three-run homer, then had an RBI double in the 10th inning that gave Pittsburgh a road win over Milwaukee.

The Pirates withstood a two-homer performance from Milwaukee’s Daniel Vogelbach to win the deciding game of this series. Pittsburgh has won two of three in each of its last three series to recover from an early six-game skid.

Pittsburgh’s Bryan Reynolds and Milwaukee’s Avisaíl García also homered.

Moran hit a leadoff double off J.P. Feyereisen (0-1) to bring home automatic runner Bryan Reynolds from second base.

METS 2, ROCKIES 1: Marcus Stroman pitched eight innings of one-run ball and made a dazzling defensive play, catcher James McCann threw out Trevor Story attempting to steal second for the final out and New York won in Denver.

J.D. Davis delivered an RBI single and Jeff McNeil had an RBI groundout for the Mets, who have won five of their last six, including two of three at Coors Field this weekend.

Charlie Blackmon had an RBI single for the Rockies, who have lost eight of nine.

Stroman (3-0) allowed three hits and struck out five. He also helped himself with a spectacular backhand play to start the eighth.

INTERLEAGUE

INDIANS 6, REDS 3: Shane Bieber kept up his record strikeout run, fanning 13 while pitching Cleveland to a win in Cincinnati.

Bieber (2-1) become the first pitcher in big league history to begin the season with four straight starts with at least 10 strikeouts.

The AL Cy Young Award winner has 48 strikeouts this year, matching Hall of Famer Nolan Ryan for the most through the first four starts of a season. Bieber has fanned at least eight in 16 straight starts, one short of Randy Johnson’s major league mark.

Bieber went eight innings, allowing three runs and six hits with two walks.

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