CHICAGO — The Cleveland Guardians are dealing with a COVID-19 outbreak that has sidelined Manager Terry Francona and several of the team’s coaches, leading to the postponement of Wednesday’s game against the Chicago White Sox.

Shortly after Francona’s positive test became known, Major League Baseball said there were “multiple positive COVID-19 tests” in Cleveland’s organization and called off Wednesday’s series finale to allow for more testing and contact tracing.

It’s the first coronavirus-related postponement since the season started on April 7.

Guardians bench coach DeMarlo Hale, who was slotted to fill in for Francona, also tested positive, and Cleveland has “multiple coaches and other team support staff members” infected with the virus, according to team spokesman Bart Swain.

There are no known current cases among Cleveland’s players. The team recently had an outbreak.

At this point, it’s unclear who will manage the Guardians when they open a three-game series in Minnesota on Friday. It’s likely the team will bring up several minor league coaches and field coordinators for the series.

First-base coach Sandy Alomar could be an option to manage. He took over those duties during the pandemic-shortened 2020 season after Francona was forced to step away after just 14 games due to a health issue.

The Guardians are off Thursday.

Francona, who has dealt with serious health problems the past two seasons, tested positive for the virus a few hours before the scheduled first pitch. The team said the 63-year-old Francona currently is not showing any symptoms.

Cleveland’s team recently had a coronavirus outbreak, with infielders Owen Miller, Yu Chang and pitchers Cal Quantrill and Anthony Castro all being placed on the COVID-19 injury list. All have returned except Chang, who is in the minors.

Also, the team’s TV broadcast crew had several members test positive during the team’s West Coast trip.

Francona had been in good health this season following two challenging years. In 2020, he was hospitalized with gastrointestinal issues. Last year, Francona struggled after undergoing offseason surgery on his foot and left the team in July.

ARBITRATION: The Atlanta Braves beat third baseman Austin Riley and the St. Louis Cardinals defeated outfielder Tyler O’Neill in the first salary arbitration decisions this year.

Riley was awarded $3.95 million rather than his $4.25 million request. Arbitrators Richard Bloch, Steven Wolf and John Woods heard the case virtually on Tuesday.

O’Neill, a two-time Gold Glove winner, was awarded $3.4 million instead of his $4.15 million request. Mark Burstein, Brian Keller and John Stout heard the case Friday.

BRAVES: Catcher Manny Pina will have season-ending surgery after tests revealed ligament and cartilage damage in his left wrist.

Braves Manager Brian Snitker said the loss of Pina means William Contreras will continue to serve as the top backup to starter Travis d’Arnaud. Contreras, 24, began the season with Triple-A Gwinnett.

Pina, 34, signed a two-year, $8 million deal with the Braves before the season.

Pina was placed on the 10-day injury list on April 28 with left wrist inflammation. After he continued to have discomfort, an MRI revealed the more serious injury that will require surgery.

Snitker said Pina is expected to be recovered in time for spring training next season.

PADRES: Manager Bob Melvin had prostate surgery Wednesday.

The team announced Melvin’s surgery during its 7-5 loss to the Chicago Cubs. It had no further details and said it likely won’t have any updates until next week.

WEDNESDAY’S GAMES

AMERICAN LEAGUE

YANKEES 5, BLUE JAYS 3: Gleyber Torres drove in all New York’s runs with a go-ahead, three-run homer off Jose Berrios in the fourth inning and a two-run single, leading the surging Yankees over visiting Toronto for their 15th win in 17 games.

An All-Star in his first two seasons who slumped in 2020 and ’21, Torres restored a two-run lead with his sixth-inning single off Trevor Richards. Torres has four home runs in his last 11 games. Overall, he is batting .222 with five homers and 18 RBI.

New York won its seventh straight series and improved to a major league-best 22-8, its best 30-game start since 2003. The Yankees are 13-0 when scoring five runs or more.

Toronto has lost a season-high four straight and seven of nine. On a sloppy day for the Blue Jays, Bo Bichette failed to advance to third on an errant pitch following his fifth-inning double. Vladimir Guerrero Jr. then struck out, slammed his bat against the ground and snapped the lumber over his left knee.

ASTROS-TWINS SUSPENDED: Houston and Minnesota had their game suspended when a severe thunderstorm rolled through and halted play in the top of the fourth inning with the Astros leading the Twins 5-1 on Jeremy Pena’s three RBI and Jose Altuve’s home run.

The teams will pick up where they left off Thursday afternoon and play the last six innings, before staging the series finale at Target Field about a half-hour after the first game concludes. Both clubs will be allowed to roster an extra 27th player for the second game.

ATHLETICS 9, TIGERS 0: Zach Logue pitched seven sharp innings in his second major league start and visiting Oakland spoiled the debut of Joey Wentz by thumping floundering Detroit.

Sean Murphy and Kevin Smith each drove in two and Christian Bethancourt supplied three hits, two runs scored and an RBI for the A’s. Ramon Laureano reached base three times, scored two runs and drove in another.

Oakland, which entered Detroit on a nine-game losing streak, is 3-1 in the five-game series. The Tigers have lost 8 of 9, scoring two runs or fewer in each of those defeats.

RAYS 4, ANGELS 2: Vidal Brujan got an RBI double leading off the 10th inning for his first hit of the season, and visiting Tampa Bay rebounded from its no-hit loss with a victory over Los Angeles.

One night after rookie Reid Detmers threw the 12th no-hitter in the Angels’ franchise history, Tampa Bay snapped its three-game skid and avoided a series sweep in the finale of a 10-game trip.

NATIONAL LEAGUE

PIRATES 5, DODGERS 3: Daniel Vogelbach hit a go-ahead homer in the seventh inning, and Pittsburgh took a series from visiting Los Angeles for the first time in nearly five years.

Vogelbach lined a shot to the seats in right field off Daniel Hudson (1-2), putting the Pirates back in front after they squandered a three-run lead in the top of the inning.

Jack Suwinski hit his second home run in three days for Pittsburgh. Josh VanMeter also homered off Dodgers reliever Tommy Kahnle in the sixth inning, but he committed an error in the seventh that helped kickstart a Los Angeles rally highlighted by Edwin Rios’ bases-clearing double off Chris Stratton.

NATIONALS 8, METS 3: Juan Soto and Nelson Cruz homered as the Nationals sent Mets right-hander Tylor Megill to the earliest exit of his career, and Washington won at home.

Soto hit a two-run homer in the Nationals’ five-run first inning and Cruz, who came in batting .170 with three homers, hit his 453rd career longball, a three-run blast to left-center in the second that traveled an estimated 436 feet.

Megill (4-2) walked the next batter and his night was over. He got four outs, allowing eight runs on eight hits with a walk and a hit batter, losing his second straight start as his ERA swelled from 2.43 to 4.41. The second-year pitcher’s previous shortest outing came Sept. 15, when he allowed six runs in three innings in a loss to St. Louis.

REDS 14, BREWERS 11: Christian Yelich hit for a record-tying third cycle – all of them against Cincinnati – but Milwaukee’s rally fell short in the ninth inning in losing at Cincinnati

Tyler Stephenson drove in four runs with a pair of doubles and Colin Moran hit a three-run homer for Cincinnati. The Reds, with the worst record in the majors, won their second straight series by topping the NL Central leaders.

Yelich became the sixth player in major league history to hit at least one home run, triple, double and a single in the same game three times. He joined Trea Turner, Adrian Beltre, Babe Herman, Bob Meusel and John Reilly in accomplishing the feat.

Yelich doubled in the first, hit a three-run homer in the third, singled in the fifth and tripled during a six-run ninth.

Hunter Renfroe hit two solo homers for the Brewers.

MARLINS 11, DIAMONDBACKS 3: Jacob Stallings hit a go-ahead single in the ninth, Jazz Chisholm Jr. followed with a three-run homer and Miami  used an eight-run final inning to win at Phoenix.

Miami controlled most of the game until the eighth, when pinch-hitter Jordan Luplow connected for a tying two-run homer against Marlins reliever Steven Okert.

Miami responded quickly – and decisively – off Mark Melancon. Stallings came into the game hitting just .183 but came up big in the ninth, hitting a single that put the Marlins back in front. Chisholm then drove a low pitch out to left-center, barely clearing the wall for a three-run blast that pushed Miami’s lead to 7-3.

GIANTS 7, ROCKIES 1: Brandon Crawford homered, leading host San Francisco past Colorado for its 10th straight win over the Rockies.

Crawford drove in three runs and scored twice as San Francisco extended its overall winning streak to five. Joey Bart, Brandon Belt, LaMonte Wade Jr. and Joc Pederson also drove in runs for the Giants.

Colorado lost its fourth in a row.

PADRES 7, CUBS 5: Alfonso Rivas hit a tie-breaking two-run single against his hometown team in the eighth inning, and banged-up Chicago won at San Diego.

Rivas, who grew up in Chula Vista and went to La Jolla Country Day, came up with the bases loaded and singled to center off Luis Garcia (0-2). Rivas hit a two-run homer in Tuesday night’s 5-4 loss that bounced out of the glove of rookie center fielder Jose Azocar and went over the fence.

NATIONALS 8, METS 3: Juan Soto and Nelson Cruz homered as Washington won at home, sending Mets right-hander Tylor Megill to the earliest exit of his career.

Soto hit a two-run homer in the Nationals’ five-run first inning and Cruz, who came in batting .170 with three homers, hit his 453rd career longball, a three-run blast to left-center in the second that traveled an estimated 436 feet.

Megill (4-2) walked the next batter and his night was over. He recorded four outs while allowing eight runs on eight hits with a walk and a hit batter, losing his second straight start as his ERA swelled from 2.43 to 4.41.

INTERLEAGUE

PHILLIES 4, MARINERS 2: Rhys Hoskins homered for the third straight game and provided all of Philadelphia’s offense with the second grand slam of his career, and the Phillies won at Seattle.

The Phillies took 2 of 3 from the Mariners helped by the homer barrage by Hoskins. He had solo homers in each of the first two games and provided the big blow with his first grand slam since March 28, 2019, against Atlanta.