Norm Macdonald, a “Saturday Night Live” cast member best known as the host of Weekend Update, died Tuesday. He was 61.

Macdonald succumbed to a nine-year cancer battle that he kept private, his management team told Deadline.

“He was most proud of his comedy,” producing partner Lori Jo Hoekstra told the outlet. “He never wanted the diagnosis to affect the way the audience or any of his loved ones saw him. Norm was a pure comic. He once wrote that ‘a joke should catch someone by surprise, it should never pander.’ He certainly never pandered. Norm will be missed terribly.”

Macdonald started his career as a writer on “Roseanne” before being hired at “SNL” in 1993, where he stayed for five years.

When Macdonald was taken off the Weekend Update desk in 1998, the network blamed low ratings, but the comedian took it personally, publicly accusing Don Ohlmeyer, the president of NBC West Coast, of firing him over jokes about O.J. Simpson.

“He thinks of himself as a straight shooter, even though he’s a liar and a thug,” Macdonald told the Daily News of Ohlmeyer in 1998.

In the later years of his career, Macdonald starred in his own comedy series, “The Norm Show,” from 1999 to 2001 and had a recurring role on “The Middle” as Mike Heck’s brother, Rusty.

He recently voiced Yaphit, a Gelatin Lieutenant, in Seth MacFarlane’s “The Orville” and was a popular guest on late night shows, particularly “The Tonight Show with Conan O’Brien.”

“I was a huge fan of Norm Macdonald and I essentially ripped off his delivery when I first started acting,” Seth Rogen tweeted. “I would stay up specifically to watch him on talk shows. He was the funniest guest of all time. We lost a comedy giant today. One of the the all time greats.”

I am absolutely devastated about Norm Macdonald. Norm had the most unique comedic voice I have ever encountered and he was so relentlessly and uncompromisingly funny. I will never laugh that hard again. I’m so sad for all of us today.

— Conan O’Brien (@ConanOBrien) September 14, 2021